Aspartate Amino Transferase (AST / SGOT)

The Aspartate Aminotransferase AST (SGOT) test determines the concentration of the AST enzyme in the blood. The test is primarily conducted to assess liver health. AST, also known as SGOT (serum glutamic-oxaloacetic transaminase), is an enzyme present in several tissues, with the highest concentrations found in the liver, heart, and muscles. It plays a vital role in amino acid metabolism by facilitating the transfer of amino groups between molecules. The AST test is typically a part of the liver function tests and is used to diagnose and monitor the progression of liver disorders. It can also be useful to detect various other health conditions. Residents who want to assess their liver health can schedule an Aspartate Aminotransferase AST (SGOT) Test at home conveniently.

The AST test assesses the levels of AST/ SGOT enzyme in the bloodstream.

In healthy individuals, AST is present in minimal quantities. With damage to the liver or any other body cells, AST levels rise as the damaged cells release this enzyme into the bloodstream. High AST levels may be associated with conditions like liver injury, muscle disorders, or other systemic health issues. Conversely, low AST levels are typically not a cause for concern and are generally considered normal.

To prepare for an AST test at home, check the following preparations:

• Prerequisites

Fasting is not required for an AST test. However, if you have existing liver disorders or any other illnesses, your doctor may recommend special instructions including fasting.

• Best Time to Get Tested

The AST test is best performed during the daytime at your convenience.

• Who Should Get an AST Test?

The AST test is advised for individuals who:

• Are being evaluated for liver health or function.

• Experience symptoms of liver issues such as jaundice, fatigue, or abdominal pain.

• Have conditions like hepatitis, fatty liver disease, or muscle disorders.

• Are undergoing treatment for liver disease to monitor progress. 1,2

• Cautions Before Taking an AST Test

Inform your doctor about any medications, supplements, or herbal products you are taking, as these may affect AST levels.

Your doctor may recommend an AST test to diagnose a potential liver disorder if you show symptoms of liver damage, such as:

• Nausea and vomiting.

• Fatigue or weakness.

• Loss of appetite.

• Jaundice (yellowing of the skin and eyes).

• Abdominal pain or swelling.

• Swollen legs or ankles.

• Dark urine or pale stool.

• Persistent itching.

Additionally, an AST test may be performed for the following reasons:

• Routine Health Evaluation : The AST test can be a part of a blood panel, e.g., a comprehensive metabolic panel to assess overall health, even in the absence of specific symptoms.

• Screening for Liver Disease : Testing is recommended for individuals with risk factors like alcohol use disorder, family history of liver disease, obesity, diabetes, or exposure to hepatitis.

• Monitoring Liver Conditions : The AST test can also be used to track the progression or improvement of liver diseases and assess the impact of treatments or medications on liver function.

• Detecting Cell Damage Beyond the Liver : While AST is primarily a marker of liver health, elevated AST levels observed during the test can also indicate damage to other organs, such as the heart or muscles.

The AST test provides crucial information for diagnosing and managing liver-related and systemic conditions, making it an essential blood test for the prevention and diagnosis of these conditions.